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AFS Glucarate Extracts

Glucarate helps the body remove harmful toxins.

Patent No: US7662863B2

Glucarate is a potent ingredient for cellular detoxification. While it is primarily used for liver health, there are several other substantial health benefits, including hormone balancing and supporting healthy cholesterol. Preventium® is also patented for recovering from the negative side effects associated with alcohol ingestion.


AFS has two high-quality and well-studied glucarate ingredients:

CDG® Calcium D-Glucarate [CDG] is more commonly used in supplemental delivery systems like capsules and tablets.

Preventium® Potassium-Hydrogen Glucarate [PHG] is a water-soluble ingredient designed for simple use with beverage and stick pack applications.

Formulation Benefits

•   Water-Soluble

•   Neutral Taste Profile

•   USP Grade

•   FCC Grade



•  Food & Beverages

•  Dietary Supplements

•  Pharmaceuticals / Injectables

•  Topical Cosmetics

Target Markets for Glucarate Products

Detoxification: Preventium® and CDG® glucarate facilitates the removal of harmful toxins via glucuronidation / Phase II detoxification pathway.

Recovery: Preventium® and CDG® glucarate are patented ingredients for recovering from the negative side effects associated with alcohol ingestion (see late-night recovery).

Liver Health, Prostate Health, & Breast Health: Preventium® and CDG® glucarate facilitates the removal of excess steroidal hormones via glucuronidation / Phase II detoxification pathway.

Healthy Cholesterol: By supporting liver health, Preventium® and CDG® glucarate has been shown to lower serum cholesterol, LDL cholesterol, and triglycerides.

Sports Nutrition Inflammation Response: Preventium® and CDG® glucarate decreases pro-inflammatory cytokines IL-6 and TNFα while increasing anti-inflammatory IL-10.

How Glucarate Works

Glucarate is a naturally occurring nutrient produced by humans. Smaller amounts are also found in fruits and vegetables. Exposure to toxic chemicals like pesticides, herbicides, plasticizers (like BPA), and air pollution are part of a long list of chemicals encountered every day at home, school, work, and around the community. One of the ways the body eliminates toxins is through the liver and the phase-II detoxification pathway. Once in the body, glucarate is metabolized into glucaric acid. The liver uses this nutrient to bond toxins into water-soluble compounds called glucuronides. Once bound, toxins are less likely to continue to damage cells and can be more easily removed from the body. Glucarate also inhibits certain enzymes, called beta-glucuronide, from separating the toxins from their bond, thus preventing toxins from being reabsorbed by the body.

Glucarate by AFS for Detoxification Infographic

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*Applied Food Sciences, Inc. does not sell products direct to consumers. This product is not to be consumed in this format but is intended for further processing or manufacturing.